A bunch of delinquent women are shipped to an island prison run by the sadistic warden Carla. Forced into situations of sexual perversion and violence and torture, the prisoners band together to try to overthrow Carla and escape the island.

Edna keeps her younger sister Millie drugged and chained to her bed. The drugs have made Millie a nymphomaniac who’s endless supply of men that Edna providers her cannot satisfy her and seeing her sister unsatisfied gets Edna off. But Edna’s main plan from all of this is to inherit her deceased parents’ fortune which is supposed to all go to Millie on her 21st birthday, so if she can prove Millie insane she will get the fortune. But when one of the men appears to satisfy Millie, Millie discovers the outside world and the two will try to stop Edna’s evil plans.

A group of female freedom-fighters led by Karine Levere is caught by the warden of a women’s prison, located somwhere in the South American jungle. None of them will reveal the secrets of their organisation or the names of their collaborators in the cities, so they are handed over to Dr. Costa who, after four years inactivity in Europe, is delighted to be able to practice his torture techniques once more. Laverne fails to resist the inhuman treatments and reveals all. The only hope of saving the organization is for the girls to warn the city cell before it’s too late. They trick the prison guard into having sex with them, knock him out and break out of prison. The warden and Dr. Costa must prevent them from revealing the practices inside the prison. The hunt is on and it’s shoot to kill…